http://www.kulan.cz/index.php?action=history&feed=atom&title=Warfarin 2026-05-05T16:34:59Z Historie editací této stránky MediaWiki 1.15.1 http://www.kulan.cz/index.php?title=Warfarin&diff=7716&oldid=prev 2018-01-10T23:05:25Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 10. 1. 2018, 23:05</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 3:</td> <td colspan="2" class="diff-lineno">Řádka 3:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(jed na krysy, levný) &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(jed na krysy, levný) &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>(''Lawarin'', ''Warfarin <del class="diffchange diffchange-inline">Orion</del>'')</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>(''Lawarin'', ''Warfarin'')</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 34:</td> <td colspan="2" class="diff-lineno">Řádka 34:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* teratogenní &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* teratogenní &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Časté interakce s jinými léčivy: <del class="diffchange diffchange-inline">(účinky warfarinu zvyšují</del>: <del class="diffchange diffchange-inline">kortikoidy</del>, <del class="diffchange diffchange-inline">alopurinol</del>, <del class="diffchange diffchange-inline">amiodaron</del>, <del class="diffchange diffchange-inline">PAD</del>, <del class="diffchange diffchange-inline">paracetamol</del>, <del class="diffchange diffchange-inline">aminopeniciliny</del>, <del class="diffchange diffchange-inline">erytromycin, klaritromycin, sulfonamidy, antimykotika, metronidazol</del>, NSA, <del class="diffchange diffchange-inline">ASA nad 3g/den, omeprazol, SSRI..)) </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">'''</ins>Časté interakce s jinými léčivy<ins class="diffchange diffchange-inline">'''</ins>: &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>&#160;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* '''ATB</ins>:<ins class="diffchange diffchange-inline">''' klaritromycin</ins>, <ins class="diffchange diffchange-inline">cotrimoxazol</ins>, <ins class="diffchange diffchange-inline">flukonazol</ins>, <ins class="diffchange diffchange-inline">fluorochinolony</ins>, <ins class="diffchange diffchange-inline">metronidazol</ins>, <ins class="diffchange diffchange-inline">chloramfenikol</ins>, <ins class="diffchange diffchange-inline">klinidamycin</ins></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">Třezalka zvyšuje degradaci warfarinu přes CYP</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* '''kortikoidy''' </ins></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>&#160;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* metotrexát</ins>, <ins class="diffchange diffchange-inline">tamoxifen</ins></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">adsorbencia snižují účinnost </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* '''</ins>NSA<ins class="diffchange diffchange-inline">'''</ins>, <ins class="diffchange diffchange-inline">paracetamol </ins></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>&#160;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* '''amiodaron'''</ins></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">ASA + NSA se nemají podávat zároveň s warfarinem </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* hypolipidemika - simvastatin, lovastatin </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* alopurinol</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* třezalka</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''KI:''' zvýšené riziko krvácení, opakované pády, nespolupráce při léčbě nebo kontrolách INR)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''KI:''' zvýšené riziko krvácení, opakované pády, nespolupráce při léčbě nebo kontrolách INR)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">(heparin a warfarin = antikoagulancia, aspirin = antiagregancia)</del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=6961&oldid=prev 2012-11-26T21:12:02Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 26. 11. 2012, 21:12</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 14:</td> <td colspan="2" class="diff-lineno">Řádka 14:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>warfarin zpočátku může být zpočátku trombogenní (protože nejdřív klesne protein C a S, dřív než II, VII, Ix, X) &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>warfarin zpočátku může být zpočátku trombogenní (protože nejdřív klesne protein C a S, dřív než II, VII, Ix, X) &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>proto se dá nejdřív <del class="diffchange diffchange-inline">clexane </del>spolu s warfarinem &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>proto se dá nejdřív <ins class="diffchange diffchange-inline">LMWH </ins>spolu s warfarinem &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 21:</td> <td colspan="2" class="diff-lineno">Řádka 21:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* terapie trombóz a tromboflebitid &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* terapie trombóz a tromboflebitid &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">* při IM možno použít k profylaxi recidiv </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>* po <ins class="diffchange diffchange-inline">metalických </ins>chlopenních náhradách</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>* po chlopenních náhradách</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''dávkování''' p.o. 1x denně tak aby bylo INR kolem 2 - 3, u starších pacientů kolem 1,6 - 2,5 a u chlopenních náhrad 3,5&nbsp; (Quick 15 – 25%) &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>'''dávkování''' p.o. 1x denně tak aby bylo INR kolem 2 - 3, u starších pacientů kolem 1,6 - 2,5 a u <ins class="diffchange diffchange-inline">metalických </ins>chlopenních náhrad 3,5&nbsp; (Quick 15 – 25%) &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>terapii je nutné ukončovat pozvolna &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>terapii je nutné ukončovat pozvolna &nbsp;</div></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 41:</td> <td colspan="2" class="diff-lineno">Řádka 40:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>adsorbencia snižují účinnost &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>adsorbencia snižují účinnost &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>ASA + NSA se <del class="diffchange diffchange-inline">nesmí </del>podávat &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>ASA + NSA se <ins class="diffchange diffchange-inline">nemají </ins>podávat <ins class="diffchange diffchange-inline">zároveň s warfarinem </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''KI:''' zvýšené riziko krvácení, opakované pády, nespolupráce při léčbě nebo kontrolách <del class="diffchange diffchange-inline">INr</del>)</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>'''KI:''' zvýšené riziko krvácení, opakované pády, nespolupráce při léčbě nebo kontrolách <ins class="diffchange diffchange-inline">INR</ins>)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=6920&oldid=prev 2012-10-12T12:17:28Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 12. 10. 2012, 12:17</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 1:</td> <td colspan="2" class="diff-lineno">Řádka 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">Kumarinový </del>derivát - nepřímé antikoagulancium <del class="diffchange diffchange-inline">(další jsou např. peletan, fenprokumol)</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">kumarinový </ins>derivát - nepřímé antikoagulancium</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>jed na krysy, levný</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">(</ins>jed na krysy, levný<ins class="diffchange diffchange-inline">) </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">(''Lawarin'', ''Warfarin Orion'')</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 13:</td> <td colspan="2" class="diff-lineno">Řádka 15:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>proto se dá nejdřív clexane spolu s warfarinem &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>proto se dá nejdřív clexane spolu s warfarinem &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=5122&oldid=prev 2011-10-30T17:23:50Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 30. 10. 2011, 17:23</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 9:</td> <td colspan="2" class="diff-lineno">Řádka 9:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>- rozdílná individuální vnímavost, nutná monitorace &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>- rozdílná individuální vnímavost, nutná monitorace &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">warfarin zpočátku může být zpočátku trombogenní (protože nejdřív klesne protein C a S, dřív než II, VII, Ix, X) </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">proto se dá nejdřív clexane spolu s warfarinem </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=4838&oldid=prev 2011-09-10T13:35:48Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 10. 9. 2011, 13:35</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 12:</td> <td colspan="2" class="diff-lineno">Řádka 12:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''užití:''' &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''užití:''' &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>* hlavně u '''fibrilace síní'''</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>* hlavně u '''fibrilace síní''' <ins class="diffchange diffchange-inline">(nad 75 let, do 75 let pokud jsou přítomny rizikové faktory TEN)</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* terapie trombóz a tromboflebitid &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* terapie trombóz a tromboflebitid &nbsp;</div></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 18:</td> <td colspan="2" class="diff-lineno">Řádka 18:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* po chlopenních náhradách</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* po chlopenních náhradách</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''dávkování''' p.o. tak<del class="diffchange diffchange-inline">, </del>aby <del class="diffchange diffchange-inline">byl Quick 15 – 25% (</del>INR kolem 2 - 3, u chlopenních náhrad 3,5) <del class="diffchange diffchange-inline">1x denně</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>'''dávkování''' p.o. <ins class="diffchange diffchange-inline">1x denně </ins>tak aby <ins class="diffchange diffchange-inline">bylo </ins>INR kolem 2 - 3, <ins class="diffchange diffchange-inline">u starších pacientů kolem 1,6 - 2,5 a </ins>u chlopenních náhrad 3,5 <ins class="diffchange diffchange-inline"> (Quick 15 – 25%</ins>) &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>terapii je nutné ukončovat pozvolna &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>terapii je nutné ukončovat pozvolna &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''NÚ:''' &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''NÚ:''' &nbsp;</div></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 27:</td> <td colspan="2" class="diff-lineno">Řádka 28:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* zpomalené hojení zlomenin &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* zpomalené hojení zlomenin &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* teratogenní &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* teratogenní &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">* </del>Časté interakce s jinými léčivy (<del class="diffchange diffchange-inline">antidiabetika</del>) &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Časté interakce s jinými léčivy<ins class="diffchange diffchange-inline">: </ins>(<ins class="diffchange diffchange-inline">účinky warfarinu zvyšují: kortikoidy, alopurinol, amiodaron, PAD, paracetamol, aminopeniciliny, erytromycin, klaritromycin, sulfonamidy, antimykotika, metronidazol, NSA, ASA nad 3g/den, omeprazol, SSRI..)</ins>) &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Třezalka zvyšuje degradaci warfarinu přes CYP</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Třezalka zvyšuje degradaci warfarinu přes CYP</div></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 34:</td> <td colspan="2" class="diff-lineno">Řádka 36:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>ASA + NSA se nesmí podávat &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>ASA + NSA se nesmí podávat &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">'''KI:''' zvýšené riziko krvácení, opakované pády, nespolupráce při léčbě nebo kontrolách INr)</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=4794&oldid=prev 2011-09-09T15:45:46Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 9. 9. 2011, 15:45</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 1:</td> <td colspan="2" class="diff-lineno">Řádka 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Kumarinový derivát - nepřímé antikoagulancium (další jsou peletan, fenprokumol)</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Kumarinový derivát - nepřímé antikoagulancium (další jsou <ins class="diffchange diffchange-inline">např. </ins>peletan, fenprokumol)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>jed na krysy, levný</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>jed na krysy, levný</div></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=4793&oldid=prev 2011-09-09T15:45:31Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 9. 9. 2011, 15:45</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 1:</td> <td colspan="2" class="diff-lineno">Řádka 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">[[Kumarinové deriváty|</del>Kumarinový derivát<del class="diffchange diffchange-inline">]] </del>- nepřímé antikoagulancium</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Kumarinový derivát - nepřímé antikoagulancium <ins class="diffchange diffchange-inline">(další jsou peletan, fenprokumol)</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">'''účinek''' - antagonizuje jaterní syntézu koagulačních faktorů (II</del>, <del class="diffchange diffchange-inline">VII, IX, X), antagonista vitaminu K (blok enzymu regenerujícího vitK)</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">jed na krysy</ins>, <ins class="diffchange diffchange-inline">levný</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''užití''' &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">'''účinek:''' - antagonizuje jaterní syntézu koagulačních faktorů (II, VII, IX, X), antagonista vitaminu K (blok vitK-reduktázy)</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">-&gt; pomalý nástup účinku </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">- rozdílná individuální vnímavost, nutná monitorace </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>'''užití<ins class="diffchange diffchange-inline">:</ins>''' &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* hlavně u '''fibrilace síní'''</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* hlavně u '''fibrilace síní'''</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=3856&oldid=prev 2011-05-09T15:17:28Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 9. 5. 2011, 15:17</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 5:</td> <td colspan="2" class="diff-lineno">Řádka 5:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''užití''' &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''užití''' &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* hlavně u '''fibrilace síní'''</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* profylaxe trombóz a embolií (po operacích) &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* hlavně u fibrilace síní</del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* terapie trombóz a tromboflebitid &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* terapie trombóz a tromboflebitid &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* při IM možno použít k profylaxi recidiv &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* při IM možno použít k profylaxi recidiv &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* po chlopenních náhradách</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''dávkování''' p.o. tak, aby byl Quick 15 – 25% (INR kolem 2 - 3, u chlopenních náhrad 3,5) 1x denně</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''dávkování''' p.o. tak, aby byl Quick 15 – 25% (INR kolem 2 - 3, u chlopenních náhrad 3,5) 1x denně</div></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 36:</td> <td colspan="2" class="diff-lineno">Řádka 37:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>čerstvá mražená plazma (během pár desítek minut obnovená normální krvácivost, např. po akutních operacích)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>čerstvá mražená plazma (během pár desítek minut obnovená normální krvácivost, např. po akutních operacích)</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">jinak warfarinizovaného pacienta nelze operovat</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Farmakologie]] &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Farmakologie]] &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Hematologie]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Hematologie]]</div></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=3185&oldid=prev 2011-01-22T05:16:34Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 22. 1. 2011, 05:16</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 37:</td> <td colspan="2" class="diff-lineno">Řádka 37:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>čerstvá mražená plazma (během pár desítek minut obnovená normální krvácivost, např. po akutních operacích)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>čerstvá mražená plazma (během pár desítek minut obnovená normální krvácivost, např. po akutních operacích)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[category:<del class="diffchange diffchange-inline">Léčiva</del>]] &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[category:<ins class="diffchange diffchange-inline">Farmakologie</ins>]] &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Hematologie]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Hematologie]]</div></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

Kulan http://www.kulan.cz/index.php?title=Warfarin&diff=2182&oldid=prev 2010-08-27T00:59:08Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 27. 8. 2010, 00:59</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 36:</td> <td colspan="2" class="diff-lineno">Řádka 36:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>čerstvá mražená plazma (během pár desítek minut obnovená normální krvácivost, např. po akutních operacích)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>čerstvá mražená plazma (během pár desítek minut obnovená normální krvácivost, např. po akutních operacích)</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[category:Léčiva]] </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[category:Hematologie]]</ins></div></td></tr> <!-- diff generator: internal 2026-05-05 16:34:59 --> </table>

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