http://www.kulan.cz/index.php?action=history&feed=atom&title=Trombocytopenie 2026-05-05T15:45:50Z Historie editací této stránky MediaWiki 1.15.1 http://www.kulan.cz/index.php?title=Trombocytopenie&diff=9026&oldid=prev 2022-04-22T10:20:06Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 22. 4. 2022, 10:20</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 13:</td> <td colspan="2" class="diff-lineno">Řádka 13:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ELFO, LDH &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ELFO, LDH &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* pro dg HIT lze imunologicky stanovit protilátky (VFN), ale může být falešná pozitivita, nebo flowcytometricky (ÚHKT)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* pro dg HIT lze imunologicky stanovit protilátky (VFN), ale může být falešná pozitivita, nebo flowcytometricky (ÚHKT)</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* beta2mikroglobulin </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* (B12, folát, TSH, metabolismus železa...)</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Coombsův test při souběžné anémii</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=9015&oldid=prev 2022-01-08T20:24:32Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 8. 1. 2022, 20:24</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 65:</td> <td colspan="2" class="diff-lineno">Řádka 65:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ev. splenektomie &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ev. splenektomie &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* destičky jen vzácně při život ohrožujících krváceních &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* destičky jen vzácně při život ohrožujících krváceních &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Doptelet (avatrombopag) tablety</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(EVANSŮV SYNDROM: ITP + autoimunitní hemolytická anemie (anemie + trombocytopenie))</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(EVANSŮV SYNDROM: ITP + autoimunitní hemolytická anemie (anemie + trombocytopenie))</div></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 172:</td> <td colspan="2" class="diff-lineno">Řádka 173:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Terapie == </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">transfúze - trombonáplava </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">'''avotrombopag''' (''Doptelet'') - p.o. přípravek k úpravě těžké trombocytopenie u pacientů s chronickým jaterním onemocněním před invazivním zákrokem</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">také k léčbě pacientů s primární chronickou imunitní trombocytopenií (ITP) refrakterních na kortikosteroidy a imunoglobuliny</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Hematologie]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Hematologie]]</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Interna]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Interna]]</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=9005&oldid=prev 2021-12-14T16:09:12Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 14. 12. 2021, 16:09</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 5:</td> <td colspan="2" class="diff-lineno">Řádka 5:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>pseudotrombocytopenie = stroj spočítá shluk trombocytů jako jedna, <del class="diffchange diffchange-inline">destičkz </del>se shluknou vlivem IgG (IgM, IgA) ve zkumavce s EDTA (fialová), kde se vychytá Ca2+ &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>pseudotrombocytopenie = stroj spočítá shluk trombocytů jako jedna, <ins class="diffchange diffchange-inline">destičky </ins>se shluknou vlivem IgG (IgM, IgA) ve zkumavce s EDTA (fialová), kde se vychytá Ca2+ &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">'''vyšetřovací plán:''' </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* KO + manuální dif., včetně retikulocytů a nezralé frakce trombocytů </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* stanovení protilátek vázaných na trombocytech FACSem </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* ELFO, LDH </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* pro dg HIT lze imunologicky stanovit protilátky (VFN), ale může být falešná pozitivita, nebo flowcytometricky (ÚHKT)</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Snížená tvorba ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Snížená tvorba ==</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=8584&oldid=prev 2018-05-23T19:58:18Z

<p><span class="autocomment">TROMBOTICKÉ MIKROANGIOPATIE: (TTP + HUS)</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 23. 5. 2018, 19:58</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 99:</td> <td colspan="2" class="diff-lineno">Řádka 99:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>vrozená nebo autoimunitně zprostředkovaná porucha v proteolytickém štěpení von Wilebrand faktoru (takže je vWF nadbytek) (enzym ADAMTS13 normálně štípe vWF, na malé neškodné kousky, ale když enzym je defektní..)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>vrozená nebo autoimunitně zprostředkovaná porucha v proteolytickém štěpení von Wilebrand faktoru (takže je vWF nadbytek) (enzym ADAMTS13 normálně štípe vWF, na malé neškodné kousky, ale když enzym je defektní..)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>velký chuchel destiček, ucpou co můžou, rozřežou erytrocyty</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>velký chuchel destiček, ucpou co můžou, rozřežou erytrocyty <ins class="diffchange diffchange-inline">(anémie)</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>u mladých dospělých vznikají podobné mikrotromby zejména v '''mozku''' (a také v ledvinách)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>u mladých dospělých vznikají podobné mikrotromby zejména v '''mozku''' (a také v ledvinách)</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* '''neurologické deficity''' </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* '''trombocytopenie''' s krvácivými projevy, '''schistocyty'''</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* horečky &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* horečky &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* trombocytopenie s krvácivými projevy</del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* mikroangiopatická hemolytická anemie &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* mikroangiopatická hemolytická anemie &nbsp;</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* neurologické deficity </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ledvinné selhání</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ledvinné selhání</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=7594&oldid=prev 2017-07-23T11:08:54Z

<p><span class="autocomment">TROMBOTICKÉ MIKROANGIOPATIE: (TTP + HUS)</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 23. 7. 2017, 11:08</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 108:</td> <td colspan="2" class="diff-lineno">Řádka 108:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ledvinné selhání</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* ledvinné selhání</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Th - plazmaferéza<del class="diffchange diffchange-inline">/velké dávky FFP</del>, do <del class="diffchange diffchange-inline">úpravy </del>klinického <del class="diffchange diffchange-inline">obrazu </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Th - plazmaferéza <ins class="diffchange diffchange-inline">(1,5 plasmatického volumu denně)</ins>, do <ins class="diffchange diffchange-inline">normalizace </ins>klinického <ins class="diffchange diffchange-inline">stavu, počtu trombocytů, hemoglobinu, LDH, neurologického postižení (úprava renálních funkcí je pozvolnější)</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">nebo velké dávky plazmy, ale to spíše iniciálně než je dostupná plazmaferéza, a kortikoidy</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>u získané formy s protilátkami imunosuprese (prednison)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>u získané formy s protilátkami imunosuprese (prednison)</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=7586&oldid=prev 2017-03-25T00:23:25Z

<p><span class="autocomment">TROMBOTICKÉ MIKROANGIOPATIE: (TTP + HUS)</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 25. 3. 2017, 00:23</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 82:</td> <td colspan="2" class="diff-lineno">Řádka 82:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=== '''TROMBOTICKÉ MIKROANGIOPATIE: (TTP + HUS)''' ===</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=== '''TROMBOTICKÉ MIKROANGIOPATIE: (TTP + HUS)''' ===</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>tvorba hyalinních destičkových trombů obklopených fibrinem v systémové mikrocirkulaci, spolu s poškozením endotelu a ERY &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">extrémně vzácné - ročně 10 případů/1 milion</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>tvorba hyalinních destičkových trombů obklopených fibrinem v systémové mikrocirkulaci, spolu s poškozením endotelu a ERY<ins class="diffchange diffchange-inline">. Nejde o přeřeyání fibrinem, ale arterioly a kapiláry jsou natolik zúžené, že smykové tření mechanicky roztrhá erytrocyty (postupně, vznikají schistocyty). (Anémie, vyšší RDW (kvůli schistocytům), vyšší LD (hemolýza zvyšuje LD), nižší haptoglobin, negativní Coombsův test, koagulace v normě</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>v důsledku spotřebování destiček při koagulačních procesech je stav doprovázen trombocytopenií</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>v důsledku spotřebování destiček při koagulačních procesech je stav doprovázen trombocytopenií</div></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 88:</td> <td colspan="2" class="diff-lineno">Řádka 90:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>mikroangiopatická hemolytická anémie, trombocytopenie a v některých případech renální selhání &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>mikroangiopatická hemolytická anémie, trombocytopenie a v některých případech renální selhání &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>může být obtížné rozlišit, zda má pacient HUS nebo TTP</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>může být obtížné rozlišit, zda má pacient HUS nebo TTP &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(destičky se nepodávají)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(destičky se nepodávají)</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=7575&oldid=prev 2017-02-19T17:23:43Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 19. 2. 2017, 17:23</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 4:</td> <td colspan="2" class="diff-lineno">Řádka 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>pseudotrombocytopenie = stroj spočítá shluk trombocytů jako jedna, destičkz se shluknou vlivem IgG (IgM, IgA) ve zkumavce s EDTA (fialová), kde se vychytá Ca2+ &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>pseudotrombocytopenie = stroj spočítá shluk trombocytů jako jedna, destičkz se shluknou vlivem IgG (IgM, IgA) ve zkumavce s EDTA (fialová), kde se vychytá Ca2+ &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Snížená tvorba ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Snížená tvorba ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''AMEGAKARYOCYTÁRNÍ TROMBOCYTOPENIE''' &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''AMEGAKARYOCYTÁRNÍ TROMBOCYTOPENIE''' &nbsp;</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=7553&oldid=prev 2017-02-11T21:49:37Z

<p><span class="autocomment">TROMBOTICKÉ MIKROANGIOPATIE: (TTP + HUS)</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 11. 2. 2017, 21:49</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 95:</td> <td colspan="2" class="diff-lineno">Řádka 95:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''Trombotická trombocytopenická purpura''' - akroangiotrombóza, Moschcowitzové</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''Trombotická trombocytopenická purpura''' - akroangiotrombóza, Moschcowitzové</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>vrozená nebo autoimunitně zprostředkovaná porucha v proteolytickém štěpení von Wilebrand faktoru (takže je vWF nadbytek) &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>vrozená nebo autoimunitně zprostředkovaná porucha v proteolytickém štěpení von Wilebrand faktoru (takže je vWF nadbytek<ins class="diffchange diffchange-inline">) (enzym ADAMTS13 normálně štípe vWF, na malé neškodné kousky, ale když enzym je defektní..</ins>)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>velký chuchel destiček, ucpou co můžou, rozřežou erytrocyty</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>velký chuchel destiček, ucpou co můžou, rozřežou erytrocyty</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=7529&oldid=prev 2017-01-30T09:28:36Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 30. 1. 2017, 09:28</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 1:</td> <td colspan="2" class="diff-lineno">Řádka 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>spontánní krvácivé projevy až při poklesu TRC cca pod 20 . 10&lt;sup&gt;9&lt;/sup&gt; &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>spontánní krvácivé projevy až při poklesu TRC cca pod 20 . 10&lt;sup&gt;9&lt;/sup&gt; &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>ale nemusí být poruchy krvácení ani při <del class="diffchange diffchange-inline">4 </del>TRC</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>ale nemusí být poruchy krvácení ani při <ins class="diffchange diffchange-inline">1 </ins>TRC</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">ne každá trombocytopenie je indikací k podání destiček </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">nejvíc petechií bude na kotnících</del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>pseudotrombocytopenie = stroj spočítá shluk trombocytů jako jedna, destičkz se shluknou vlivem IgG (IgM, IgA) ve zkumavce s EDTA (fialová), kde se vychytá Ca2+ &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>pseudotrombocytopenie = stroj spočítá shluk trombocytů jako jedna, destičkz se shluknou vlivem IgG (IgM, IgA) ve zkumavce s EDTA (fialová), kde se vychytá Ca2+ &nbsp;</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan http://www.kulan.cz/index.php?title=Trombocytopenie&diff=7092&oldid=prev 2013-03-16T18:14:08Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 16. 3. 2013, 18:14</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 1:</td> <td colspan="2" class="diff-lineno">Řádka 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>spontánní krvácivé projevy až při poklesu TRC pod 20 . 10&lt;sup&gt;9&lt;/sup&gt;<del class="diffchange diffchange-inline">, tak je třeba terapie </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>spontánní krvácivé projevy až při poklesu TRC <ins class="diffchange diffchange-inline">cca </ins>pod 20 . 10&lt;sup&gt;9&lt;/sup&gt; &nbsp;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">ale nemusí být poruchy krvácení ani při 4 TRC</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>(50 TRC je ok)</div></td></tr> <!-- diff generator: internal 2026-05-05 15:45:50 --> </table>

Kulan